Uses of Sildenafil

Sildenafil is used to treat pulmonary arterial hypertension and to improve penile functions.

Therapeutic Category

Sildenafil: Phosphodiesterase type 5 (PDE 5) inhibitors

How Sildenafil works

Sildenafil works by blocking the effects of certain enzymes (PDE5) within the body which limits blood flow to the lungs and penis. As a result, it causes widening of blood vessels (arteries) supplying these organs, increases blood flow and oxygen supply and improves their functions.

Common side effects of Sildenafil

• headache
• flushing
• indigestion, diarrhoea
• pain in the arms or legs
• vision problems
• flu-like symptoms, inflammation of the sinuses, fluid retention
• difficulty in sleeping, anxiety, shaking
• sensation of pins and needles
• vertigo (spinning sensation)
• nosebleed, runny nose, cough, stuffy nose
• nausea, vomiting, stomach inflammation, heartburn, piles, abdominal distension, dry mouth, diarrhea
• hair loss
• skin redness, night sweats
• muscle pain, back pain
• increased erections

When to consult your doctor

Consult your doctor if you experience:

• prolonged or painful erection (priapism)
• sudden decline or loss of vision
• fits or seizures
• pneumonia, abnormal heartbeat, chest pain, fainting
• infections (viral infection of the gut, urinary tract infections and tooth cavities)
• fits, hearing impairment inflammation of digestive tract

Health Tips for Sildenafil

• Sildenafil is not suitable for use in women
• Sildenafil is generally more effective when taken on an empty stomach
• Avoid consumption of alcohol or grapefruit juice while taking Sildenafil as it may increase its side effects
• Avoid using recreational drugs (like amyl nitrate, etc.) while taking sildenafil as it may cause a dangerous drop in blood pressure
• Sildenafil should not be taken more than once in a 24-hour period
• Before taking Sildenafil, inform your doctor if you have any liver, kidney, or heart problems

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Health Tips for Erectile dysfunction

• Erectile dysfunction
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SA CDC guidelines

Precautions: drink plenty of water

Sildenafil, a PDE5 inhibitor, begins to act in the body after a meal. It changes the composition of the phosphodiesterase (PDE-5) enzyme (which affects the cyclic enzyme (PDE-6) which makes muscles (adenosine triphosphate (ADOCKATI))). This allows more blood to flow into the penile tissue of those who are unable to eat, maintain a consistent supply of blood.

Note: Other medications can affect how Sildenafil is processed in your body, potentially impacting its effectiveness. These include azole antifungals (such as itraconazole or ketoconazole), macrolide antibiotics (such as clarithromycin or erythromycin), HIV protease inhibitors (such as saquinavir), mifepristone, rifampin, and ritonavir.

Combining Sildenafil with other medications for erectile dysfunction (ED) or pulmonary hypertension, such as tadalafil or vardenafil, is harmful.

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• Alterations can result in reduced blood pressure and dizziness consciousness.
• Rare but serious side effects include chest pain, fainting, heart attack, and the like.

These list don’t include all medications that cause or can cause side effects. If you’re not sure whether any symptoms you have may or may not be related to Sildenafil or any medications you are taking, contact your doctor or pharmacist.

Major side effects

Certain medications that can interact with Sildenafil include:

• Nitrates
• Alpha-blockers
• Diabetes medicines (such as glargine or glipizide)
• CYP3A4 inhibitors (such as ketoconazole, itraconazole, or darfilacin)
• Other medications for erectile dysfunction (ED)

Unknown medication side effects

Not a complete list

Avoid interactions with Sildenafil

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Other medications that can interact with Sildenafil include:

• Other nitrates (such as isosorbide dinitrate, isosorbide mononitrate, nitroglycerin, or nitrofurantoin)
• Nitrates including amyl nitrite, butyl nitrite, ELF, isosorbide mononitrate,ivalpropion, and nicorandil
• Other medications that may interfere with Sildenafil’s mechanism of action (such as riociguat)

Never use Sildenafil

A dangerous drop in blood pressure arises when Sildenafil is used with nitrates. This can lead to dizziness or fainting. A lower dose of Sildenafil prescribed by the doctor may help.

Avoid using Sildenafil with nitrates used for treating chest pain.

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• A rare side effect of Sildenafil is a sudden decrease in blood pressure that can lead to dizziness or fainting.
• A rare side effect of Sildenafil is cardiovascular collapse when Sildenafil is used with beta-blockers, including metoprolol and sotalol.
• A rare side effect of Sildenafil is a sudden loss of vision in one or both eyes. This may be a sign of a serious eye problem.

What is Sildenafil?

Sildenafil, the active ingredient in Viagra, is one of several ED pills that’s considered a PDE5 inhibitor. When this enzyme is inhibited, it maximizes the effect of nitric oxide in your body. (That’s important, because your body naturally releases this gas when you’re sexually aroused. So it’s key to the process of getting and maintaining an erection.)

With more nitric oxide in play, the muscles around your penis can relax. In turn, blood flow to your penis improves. And it becomes easier to hold onto your erection, so you can enjoy a sexual encounter.

Sildenafil also works quickly. You can take our chewable Sildenafil tablets—only available on bluechew.com—about one hour before sex. Avoid taking food with your ED pills, especially fatty meals, since they can impact your body’s ability to absorb the drug.

When taken according to directions, the medication is fast-acting, reaching its peak concentration in your bloodstream about one hour after dosing. Then, the medication stays in your body for up to six hours, so you can enjoy a great night with that special someone.

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How it Works:

1. Works:In our clinical laboratory, we’ve studied the ability of sildenafil to block PDE5, allowing the smooth muscles in your penis to relax. That allows blood to reach your penis and get into your penis before you can develop a erection.

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Key Takeaways:

• Sildenafil:Inhibits PDE5 to improve erections.
• Possible Side Effects:Cardiovascular and Allergic Reactions.
• One of the advantages:

Take Viagra exactly as it was prescribed for you. Do not take more than the prescribed dose per day, or you and your doctor may not be able to tell you what you can and can’t eat or drink.

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Disclaimer:

Like all medicines, Viagra may cause side effects, but not everyone gets them. Although some side effects can be mild, not every drug produces them. If you experience any serious or unexpected symptoms, you should contact your doctor immediately.

If you are taking any other medications, including any that you buy without a prescription, you may encounter some side effects. These include:

• Allergy-like reactions
• Heartburn-like reactions
• Nausea
• Vomiting

If you are experiencing any other condition, especially heart problems, you should do not take Viagra. Also, do not take Viagra if you are also using a migraine drug or if you have diabetes.

Sildenafil citrate, commonly known by the brand name, is a prescription-only medicine used to treat erectile dysfunction (ED) in adult men. It works by improving blood flow to the penis, helping to achieve and maintain an erection during sexual activity.

Dosage and Administration

Sildenafil is available in 25mg, 50mg, and 100mg strengths.

• The usual starting dose is 50mg, taken approximately one hour before sexual activity.
• Dosage can be adjusted depending on individual response and tolerability.
• Take only one tablet in 24 hours, with or without food.
• Avoid grapefruit juice, as it can increase the risk of side effects.
• A high-fat meal may delay onset of action.

Effectiveness

Sildenafil has been shown to be effective in up to 80% of men with ED, with effects typically noticeable within 30 to 60 minutes, and lasting for up to 4–5 hours.

Side Effects

Common side effects include:

• Headache
• Flushing
• Nasal congestion
• Indigestion

Less common but serious effects include visual disturbances, hearing changes, or prolonged erections. Seek medical attention if severe or persistent side effects occur.

Contraindications

Sildenafil should not be used by those:

• Taking nitrates for chest pain
• With severe heart or liver conditions
• Under 18 years of age
• With certain medication interactions (e.g. alpha-blockers, antifungals, antibiotics)

Interactions

Inform your doctor of all medications and supplements before use. Interactions may occur with:

• Nitrates
• Alpha-blockers
• Some antibiotics and antifungal medicines

Alcohol and Heart Conditions

Avoid excessive alcohol while taking sildenafil, as it can lower blood pressure and increase side effect risk. Use with caution if you have any heart-related conditions.

Availability and Cost

Sildenafil is available by prescription only in the UK.

• Generic versions are more affordable than branded Viagra.
• Supplied by licensed UK pharmacies such as Online Chemist.
• Avoid counterfeit products from unregulated websites.

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Consult your GP for further advice.

Get Your Private MessageAbout Sildenafil

Sildenafil belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors. It works by increasing blood flow to the penis, helping to achieve and maintain an erection during sexual activity.

Please note, our online pharmacy is not responsible for, nor is sufficient, the use of this medication by individuals on our site.

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Our service is only available through our online pharmacy. To make sure you are a suitable candidate for our service, you must have a diagnosis of erectile dysfunction.

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Sildenafil citrate (100mg) is the best medicine for men who want to improve their sex life. Men need to keep their erection hard and maintain it for a long time. Men can take Sildenafil 100 mg on an empty stomach or with a meal. Sildenafil citrate works in the brain. It works by increasing blood flow to the penis. It works for two hours to help men with erectile dysfunction (impotence).

It works for two hours to help men with erectile dysfunction. Sildenafil works for up to two weeks.

Sildenafil citrate

The most common side effects of Sildenafil citrate are headache, facial flushing, upset stomach, nasal congestion, and a stuffy nose. If you notice any of these symptoms, contact a doctor immediately.

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Sildenafil citrate is the best medicine for men who want to improve their sex life.

It works for up to two weeks.

It is important to note that this is not a comprehensive list of medications, but rather a summary of the drugs most commonly prescribed for erectile dysfunction.

The drugs listed below are commonly prescribed for the treatment of erectile dysfunction:

The most commonly prescribed drugs for erectile dysfunction include:

• Viagra (sildenafil)
• Sildenafil (tadalafil)
• Cialis (tadalafil)
• Levitra (vardenafil)

The drug is also used to treat pulmonary arterial hypertension.

Other drugs that are commonly used to treat erectile dysfunction include:

Other drugs that are commonly prescribed to treat erectile dysfunction include:

• Erectile dysfunction medication (Viagra)
• Tadalafil (tadalafil)
• Avanafil (adalafil)
• Tadalafil (vardenafil)

It is important to note that not all erectile dysfunction drugs are effective and that each drug may have different benefits and side effects.

The following drugs are available in Canada:

The following drugs are available in the U. S.:

Other drugs that are commonly prescribed for erectile dysfunction include: